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Where do these stem cells originate from?

Where do these stem cells originate from?

These mesenchymal stem cells come from within the body from our own adipose tissue or what we call fat cells,and from bone marrow, which are present in the spongy part of bones according to the trials of medical researchers. We can also extrapolate stem cells from the umbilical cord of newborns, which are the least risky and reliable source of stem cells. Stem cells from an adult bone marrow or fat is taken from a patient’s bone marrow, which is present in soft bones but mostly we take it from areas near the buttocks i.e iliac crest. Said areas pierce the periosteum of the iliac crest and extract the bone marrow from it, which contains stem cells. They are then infused into the area where healing is required. These stem cells pick up the signals from damaged cells, and they get the properties of surrounding cells to activate progenitor cells. Afterward, they stimulate the formation of new healthy cells. However, adult bone marrow can present a risk of having damaged stem cells, which estimate to be 100,000 in number. Consequently, this option is not widespread now.

Another option we have in acquiring stem cells is via the umbilical cord, which is considered to be the safest and most reliable way to get stem cells. They are widely used and approved by the FDA. The FDA recently approved umbilical cord stem cells and confirmed that the safest way to get stem cells is via umbilical cord derived blood forming stem cells, which are used for certain purposes by specialists. We have knowledge of bountiful advantages through stem cell therapy. Nonetheless, there are currently thousands of experiments that are undergoing trials to meet the standards of FDA in regards to gaining complete approval.

Another option we have in acquiring stem cells is via the umbilical cord, which is considered to be the safest and most reliable way to get stem cells. They are widely used and approved by the FDA. The FDA recently approved umbilical cord stem cells and confirmed that the safest way to get stem cells is via umbilical cord derived blood forming stem cells, which are used for certain purposes by specialists. We have knowledge of bountiful advantages through stem cell therapy. Nonetheless, there are currently thousands of experiments that are undergoing trials to meet the standards of FDA in regards to gaining complete approval.

In addition, this method is easier to retrieve the cells, as it is non-invasive. Umbilical cords generate a large number of mesenchymal cells MSCs because they  have the ability to partially or completely suppress the immune response i.e immunosuppressive properties.

We get the stem cells from pregnant women who decide that they don’t want to have their  unborn child’s umbilical cord. Her obstetrician asks her if she wants to donate it, then she is asked to sign a consent form, and after that she undergoes a blood test and a review of her social and medical history. Now, she has become a verified donor. After the birth of her baby, the umbilical cord of that new born is put in a sterile cord blood collection pouch and is sent to the

lab for further processing. Within the 48 hours after taking out that cord, it is processed with proprietary methods. After the lab procedures are complete, the umbilical cord stem cells are ready to be distributed.
Stem cell therapy can help to treat patients with heart problems which will be docked with other cells of heart that will get signals of damage from near by area and then stimulate the progenitor cells which are specific to create only heart cells and then they will generate proteins that will regenerate cells that are healthy and perform heart function normally. Stem cell therapy will help to improve the muscles of heart, it will
improve the coordination of nerve impulses going from heart to brain and hence will prevent heart attacks and probably other heart diseases too.
Moreover, stem cells help to treat patients with arthritis. We all have stem cells in our joints that repair the damaged cells in our joints to keep them from functioning normally and maintain their range of moment. Thus, when a patient comes to a therapist with arthritis to get stem cell therapy. The therapist takes the stem cells from the donor and infuses them via injection into the joint of the patient. The injection takes very little time. The duration of said therapy procedures vary depending on the amount of stem cells required for each patient, as well as the severity of joint

Then, the healing begins, but the speed of regeneration depends on factors, such as: the patient’s body, genetics, age, and severity of damage.

Diabetes is still considered as an incurable disease which affects millions of people. Diabetes mellitus, is a condition wherein the  pancreas doesn’t produce the  required amount of insulin as a response to glucose. As a result, this condition leads to increased glucose levels in the  human body. Insulin is produced by beta cells in the pancreas, which are rejected by the immune system of the body and are destroyed as an immune response. In turn, the outcome leads to diabetes. At present, scientists are able to produce beta cells in labs from the pluripotent (the cells which have potential to convert in any form of cell) embryonic cells, which are infused into rats. The results of these trials  have shown an

increase in the amount of insulin in said rats, of which were prior unable. These experiments have  not been performed on humans yet because of the autoimmune response that will destroy those beta cells. Consequently, researchers are working on it to make a barrier on these beta cells to produce the required amount of insulin. Ultimately, stem cell therapy is a hope for diabetic patients to get their disease treated and give those

patients a healthy and normal life.

Stem cell therapy has other advantages too, which includes the immune response that catalyzes the stem cells to respond really well to infections. Moreover, stem cells  can recollect the location of the former encounters of infections that occurred in the body. In addition, stem cells  lower the risk of manifesting teratoma, which is a rare type of tumor occurring in females. Teratomas are  fully developed tumors  found in tail bones, testicles, and ovaries. Stem cells also eliminate the risk of unwanted immune response, and hence, and self-sustain in the body. Another benefit of stem cell therapy is that it is a non-invasive method, meaning  we don’t need to put any instruments inside the body like that of surgery. Consequently, it has low risk of infection. Like everything in the world, there are advantages and disadvantages. Along with the myriad benefits and enormous healing abilities of stem cells and stem cell therapy, there are also potential side effects, too.

Adult stem cell therapy

Adult stem cell therapy has shown complications in the body when stem cells of a patient’s own body are taken. It can cause bleeding, anaemia, different types of infection, inflammation of lungs and lives, graft failure, and even liver damage, too. Donor stem cells can cause various diseases too, which include that it can cause graftversus host disease, leading throat swelling and hair loss due to the rejection of graft. However, these side effects are curable with a range of antibiotics, antibacterial, antifungal, antiviral drugs, as well as steroids that weaken the immune system. With the help of this method, we can treat different diseases; we can repair torn tissues, cartilage,ligaments in different bones, and much more. This technique will take medical science to the new advancements without a doubt. Specialists are telling us the advantages of IV stem cell therapy, which must be done under their professional observation and proficiency. In 2018 ,the director of FDA’s research said that the organization will be giving new concepts to small researchers and agencies of whom can get their approval by seeking the ways to meet their standard. Ultimately, stem cell therapy needs further advancements in this field to meet their requirements and standards to get their 100% approval.

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